Oncogynaecological Centers
Oncogynecological Center, Department of Obstetrics and Gynecology, Charles University
Czech Republic
Apolinarska 18
128 00 Prague
www.onkogyn.cz
Head of the centre
David Cibula
david.cibula@iol.cz
Staff
Zikán Michal (michal.zikan@lf1.cuni.cz)
Freitag Pavel
Sláma Jiří
Pinkavová Ivana
Janoušek Miloslav
Pavlišta David
New cancer cases per year 2007
Endometrial cancer: 108
Epithelial ovarian cancer: 134
Cervical cancer: 126
Vulvar cancer: 7
Breast cancer: 62
Total: 488
Radical surgical procedures per year 2007
Breast cancer surgery: yes
Laparoscopic lymphadenectomy: yes
Breast cancer surgery performed: yes
Laparoscopic radical hysterectomy: yes
Pelvic exenteration: yes
Robotic surgery: no
Total: 362
Accreditation in oncogynaecology
ESGO / EBCOG
Research interests
1) radical surgery
2) ultrasound in oncogynecology
3) hereditary breast/ovarian cancer
Top 5 papers in last 5 years
1) Cibula D, Slama J, Fischerova D. Update on abdominal radical trachelectomy. Gynecol Oncol. 2008 Aug 25.
2) Fischerova D, Cibula D, Stenhova H, Vondrichova H, Calda P, Zikan M, Freitag P, Slama J, Dundr P, Belacek J. Transrectal ultrasound and magnetic resonance imaging in staging of early cervical cancer. Int J Gynecol Cancer. 2008 Jul-Aug;18(4):766-72. Epub 2007 Sep 24.
3) Antoniou AC, Sinilnikova OM, Simard J, Léoné M, Dumont M, Neuhausen SL,
Struewing JP, Stoppa-Lyonnet D, Barjhoux L, Hughes DJ, Coupier I, Belotti M, Lasset C, Bonadona V, Bignon YJ; Genetic Modifiers of Cancer Risk in BRCA1/2 Mutation Carriers Study (GEMO), Rebbeck TR, Wagner T, Lynch HT, Domchek SM, Nathanson KL, Garber JE, Weitzel J, Narod SA, Tomlinson G, Olopade OI, Godwin A, Isaacs C, Jakubowska A, Lubinski J, Gronwald J, Górski B, Byrski T, Huzarski T, Peock S, Cook M, Baynes C, Murray A, Rogers M, Daly PA, Dorkins H; Epidemiological Study of BRCA1 and BRCA2 Mutation Carriers (EMBRACE), Schmutzler RK, Versmold B, Engel C, Meindl A, Arnold N, Niederacher D, Deissler H; German Consortium for Hereditary Breast and Ovarian Cancer (GCHBOC), Spurdle AB, Chen X, Waddell N, Cloonan N; Kathleen Cuningham Consortium for Research into Familial Breast Cancer (kConFab), Kirchhoff T, Offit K, Friedman E, Kaufmann B, Laitman Y, Galore G, Rennert G, Lejbkowicz F, Raskin L, Andrulis IL, Ilyushik E, Ozcelik H, Devilee P, Vreeswijk MP, Greene MH, Prindiville SA, Osorio A, Benitez J, Zikan M, Szabo CI, Kilpivaara O, Nevanlinna H, Hamann U, Durocher F, Arason A, Couch FJ, Easton DF, Chenevix-Trench G; Consortium of Investigators of Modifiers of BRCA1/2(CIMBA). RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies. Am J Hum Genet. 2007 Dec;81(6):1186-200. Epub 2007 Oct 16.
4) Zikan M, Pohlreich P, Stribrna J, Kleibl Z, Cibula D. Novel complex genomic rearrangement of the BRCA1 gene. Mutat Res. 2008 Jan 1;637(1-2):205-8. Epub 2007 Aug 7.
5) Fischerova D, Cibula D, Dundr P, Zikan M, Calda P, Freitag P, Slama J. Ultrasound-guided tru-cut biopsy in the management of advanced abdomino pelvic tumors. Int J Gynecol Cancer. 2008 Jul-Aug;18(4):833-7. Epub 2007 Aug 30.
Available position for Ph.D. students - yes
Requirements: Ph.D. in molecular oncology - genomics of sporadic and hereditary ovarian cancer with respect to prognostic and predictive factors.
Contact person: Michal Zikán, michal.zikan@lf1.cuni.cz
Last update: December 8, 2008